How to Mass Spec Your TLC Spots

Using Thomson Filter Vials

  1. After eluting analytical TLC plates, scrape-off desired spots into Thomson Shell Vial
  2. Add 0.4 mL EtOAc to Shell Vial
  3. Next, insert Plunger, press half way down and shake or swirl to extract compound from silica gel
  4. Press down plunger completely to filter sample
  5. Same Filter Vial straight to Mass Spec
Applicable Notes: