Title

Optimizing Plasmid Yields - Impact of Flask Design, Media Type and Shaking Parameters

Description

We examine the influence of culture media, vessel design, fill volume and shaking speed on bacteria and pDNA yields. We illustrate how larger production range can be obtained by using the appropriate combination between a large incubated shaker, optimized culture conditions and specifically-designed culture flasks.

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Optimizing Plasmid Yields - Impact of Flask Design, Media Type and Shaking Parameters

Blandine Vanbellinghen1, Silvia Tejerina1, Aurelie Tacheny1, Ines Hartmann2
1Eppendorf Application Technologies, S.A., Namur, Belgium
2Eppendorf SE, Hamburg, Germany

We examine the influence of culture media, vessel design, fill volume and shaking speed on bacteria and pDNA yields. We illustrate how larger production range can be obtained by using the appropriate combination between a large incubated shaker, optimized culture conditions and specifically-designed culture flasks.

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