Title
Process development for production of nonoriginator NISTmAb from CHO and NS0 cell lines
Description
We identified agitation rates and gassing strategy as critical process parameters for NISTCHO stirred-tank bioreactor operations and established processes for fed-batch and perfusion rocking bioreactor operations. We anticipate this work to benefit the growing number of researchers employing non-originator NISTmAb-expressing cell lines to support ...
Products Used in Application
24-Well Plate | 10.4mL
Square Well, Round Bottom | Sterile
pn#931568
Optimum Growth® 125mL Flask
PTFE 0.2µm Vent Cap for Increased Aeration | Sterile
pn#931110
Optimum Growth® 500mL Flask
PTFE 0.2µm Vent Cap for Increased Aeration | Sterile
pn#931112
Optimum Growth® 2.8L Flask
PTFE 0.2µm Vent Cap for Increased Aeration | Sterile
pn#931114
Related Products
Process development for production of nonoriginator NISTmAb from CHO and NS0 cell lines
Kohnhorst (2025) Process development for production of non-originator NISTmAb from CHO
and NS0 cell lines, mAbs, 17:1, 2505088, DOI: 10.1080/19420862.2025.2505088
We identified agitation rates and gassing strategy as critical process parameters for NISTCHO stirred-tank bioreactor operations and established processes for fed-batch and perfusion rocking bioreactor operations. We anticipate this work to benefit the growing number of researchers employing non-originator NISTmAb-expressing cell lines to support precompetitive innovation in biomanufacturing.