Time and Cost Effective Methods for Reducing Background Noise and Signal Suppression in Problem Matrices for Residue Analysis by LC-MS/MS

Poster presented at NACRW 2016
Joseph Kolb1, Ariana Ramdin1, Ryan Undeen1, Dennis Peterson2, Sam Ellis2 Lisa Wanders2
1Merieux NutriSciences Corporation, Gainsville, FL 32607
2Thomson Instrument Company, Oceanside, CA 92054

Several clean-up methods are compared for background reduction, analyte recovery, and cost effectiveness in order to successfully analyze a wide variety of multiclass multiresidues in difficult matrices including Chili Powder and Tobacco. The most critical aspects of reliable multiresidue analysis are the reduction of interferences from the sample matrix and analyte recovery. eXtreme|FV® , were compared to an existing ISO accredited QuEChERS method, as well as a dilute and shoot approach are analyzed in conjunction with different filtration techniques for residue analysis by LC-MS/MS for minimal number of steps, speed, reduced reagent use and reduced cost.

Related Application Notes

Time and Cost Effective Methods for Reducing Background Noise and Signal Suppression in Problem Matrices for Residue Analysis by LC-MS/MS

Several clean-up methods are compared for background reduction, analyte recovery, and cost effectiveness in order to su...

See Application Note

Title

Time and Cost Effective Methods for Reducing Background Noise and Signal Suppression in Problem Matrices for Residue Analysis by LC-MS/MS

Description

Several clean-up methods are compared for background reduction, analyte recovery, and cost effectiveness in order to successfully analyze a wide variety of multiclass multiresidues in difficult matrices including Chili Powder and Tobacco. The most critical aspects of reliable multiresidue analysis are the reduction of interferences from the sample...

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Product Used

eXtreme|FV® - PVDF 0.2µm

Pre-Split Septum, Red Cap

pn#85531-200

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