Fast and Simple Creatinine Determination in Wastewater by Liquid Chromatography-Mass Spectrometry

Nicole Centazzo1, Bonnie-Marie Frederick1, Daniel Korostyshevsky2, Lisa Wanders2, Marta Concheiro-Guisan1
1Department of Sciences, John Jay College of Criminal Justice, City University of New York, New York, NY 2Thomson Instrument Company, Oceanside, CA

A fast and simple method was developed to determine creatinine in wastewater samples with high sensitivity (LOQ 0.01 μg/mL) and specificity (2 MRM transitions per analyte). The developed method could be applied to urine samples (dilution cut-off 20 mg/dL) as well. Creatinine was detected in all authentic wastewater samples with concentrations from 0.22 to 2.68 μg/mL, and it should be further investigated as a normalization factor in wastewater analysis.

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Title

Fast and Simple Creatinine Determination in Wastewater by Liquid Chromatography-Mass Spectrometry

Description

A fast and simple method was developed to determine creatinine in wastewater samples with high sensitivity (LOQ 0.01 μg/mL) and specificity (2 MRM transitions per analyte). The developed method could be applied to urine samples (dilution cut-off 20 mg/dL) as well. Creatinine was detected in all authentic wastewater samples with concentrations from...

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Product Used

Standard|Filter Vial - PTFE 0.2µm

Pre-Split Septum, Green Cap

pn#35530-200

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