Presented at Systems Biology for Clinical Infectious Diseases Research Symposium 2019 Demand for high-throughput sample processing technologies will increaseas LC-based methods become more prevalent in academic and clinical microbiological research labs. Filter sterilization steps are required during the processing of microbiological samples because of the following. i) many bacteria and fungi are BSL2/3 level pathogens; ii) used broth media tend to contain solids; and,iii) chromatographic column longevity is required in a high-throughput laboratory. Introduction Project Aims